In the era of modern reproductive science, one of the most powerful advancements we have today is PGT in IVF. When you are on your IVF journey, this genetic test helps you choose the healthiest embryos for transfer.
Preimplantation Genetic Testing (PGT) is a method that is used in conjunction with IVF to select the healthiest embryos for transfer before implantation. This method helps to improve chances of pregnancy and reduce the high risk of miscarriage.
Types of PGT Testing:
There are mainly three types of PGT Testing-
- PGT-A (Preimplantation Genetic Testing for Aneuploidy)
- PGT-M(Preimplantation Genetic Testing for Monogenic Disorders)
- PGT-SR(Preimplantation Genetic Testing for Structural Rearrangements)
PGT-A (Preimplantation Genetic Testing for Aneuploidy):
This is the most common type of genetic testing. It generally detects conditions where the number of chromosomes is abnormal such as Down Syndrome, where there is an extra chromosome 21, or Turner syndrome, where there is only one X chromosome present in a female’s body.
PGT-M(Preimplantation Genetic Testing for Monogenic Disorders):
In this genetic screening, the embryos that carry genes with any genetic disorder are detected and the healthiest embryos are selected for transfer. PGT-M is ideal for those couples who carry such conditions which can be passed on to their children.
PGT-SR(Preimplantation Genetic Testing for Structural Rearrangements):
Structural chromosomal abnormalities such as translocation or inventions often lead to higher chances of miscarriage or infertility. Embryos that carry these structural abnormalities are identified and the embryos that are more likely to result in a successful pregnancy are selected by fertility specialists.
Benefits of PGT in IVF:
- Higher success rates: Choosing chromosomally normal embryos increases the chances of successful implantation.
- Lower risk of miscarriage: Genetic issues are a common cause of pregnancy loss; detecting them early helps avoid heartbreak.
- More confident embryo selection: Instead of guessing, you get scientifically guided choices.
- Safer single-embryo transfer: With PGT-tested embryos, you can often transfer just one embryo with greater confidence.
- Reduced risk of inherited disorders: PGT can identify specific genetic conditions that might run in a family.
PGT in IVF is especially recommended for:
- Women above 35
- Couples with a history of recurrent pregnancy loss
- Parents who are carriers of known genetic conditions
- Couples with multiple failed IVF cycles
- Cases of severe male-factor infertility
If you aren’t sure whether you fall into these categories, don’t worry, personalized guidance is key, and that’s where Dr.Sharmistha’s expert consultation helps.
PGT in IVF (Preimplantation Genetic Testing) is more than just an advanced laboratory step, it’s a way to bring clarity, confidence, and hope into your fertility journey. By helping identify the healthiest embryos, PGT can improve IVF success rates, reduce the risk of miscarriage, and support safer, more informed decisions. While it may not guarantee pregnancy, it gives couples a better chance at achieving the healthy baby they dream of.
With expert guidance and the right fertility care, PGT can become a powerful part of your personalized IVF plan. If you’re considering IVF or exploring ways to enhance your chances, consult a fertility specialist like Dr. Sharmistha who can help you understand whether PGT is the right choice for you.
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